Preparing the Vaccine

Follow strict aseptic medication preparation practices.

  • Use a new, sterile needle and syringe for each injection

Perform hand hygiene before preparing vaccines.

Prepare vaccines in a designated, clean medication area that is not adjacent to areas where potentially contaminated items are placed.

Healthcare professionals should only administer vaccines they have prepared.

Always follow the vaccine manufacturer’s directions.

nurse washing hands


ACIP General Best Practice Guidelines for Immunization

CDC vaccine preparation and administration training and clinical materials




Page last reviewed: September 27, 2021