Janssen COVID-19 Vaccine Adverse Reactions and Events

Common side effects at the injection site:

  • Pain
  • Swelling
  • Redness

Common systemic side effects:

  • Tiredness
  • Headache
  • Muscle pain
  • Chills
  • Fever
  • Nausea

Additional adverse reactions, some of which may be serious, may become apparent with more widespread use of the Janssen COVID-19 Vaccine.


Vaccine Adverse Event Reporting System

ACIP General Best Practice Guidelines for Immunization; Preventing and Managing Adverse Reactions



Page last reviewed: November 16, 2021