Janssen COVID-19 Vaccine Adverse Reactions and Events

The most common adverse reactions reported after vaccination are:
• Injection site pain 48.6%
• Headache 38.9%
• Fatigue 38.2%
• Myalgia 33.2%
• Nausea 14.2%


Additional adverse reactions, some of which may be serious, may become apparent with more widespread use of the Janssen COVID-19 Vaccine.  

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Vaccine Adverse Event Reporting System

ACIP General Best Practice Guidelines for Immunization; Preventing and Managing Adverse Reactions


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Page last reviewed: August 23, 2021