Wong-EY; Ray-R; Gao-DL; Wernli-KJ; Li-W; Fitzgibbons-ED; Camp-JE; Heagerty-PJ; De Roos-AJ; Holt-VL; Thomas-DB; Checkoway-H
Am J Ind Med 2010 May; 53(5):497-505
BACKGROUND: Strenuous occupational physical activity and physical demands may be risk factors for adverse reproductive outcomes. METHODS: A retrospective study in the Shanghai, China textile industry study collected women's self-reported reproductive history. Occupational physical activity assessment linked complete work history data to an industry-specific job-exposure matrix. Odds ratios (OR) and 95% confidence intervals (CI) were estimated by multivariate logistic regression for the first pregnancy outcome and utilized generalized estimating equations to consider all pregnancies per woman. RESULTS: Compared with women employed in sedentary jobs, a reduced risk of miscarriage was found for women working in jobs with either light (OR 0.18, 95% CI: 0.07, 0.50) or medium (OR 0.24, 95% CI: 0.08, 0.66) physical activity during the first pregnancy and over all pregnancies (light OR 0.32, 95% CI: 0.17, 0.61; medium OR 0.43, 95% CI: 0.23, 0.80). Frequent crouching was associated with elevated risk (OR 1.82, 95% CI: 1.14, 2.93; all pregnancies per woman). CONCLUSIONS: Light/medium occupational physical activity may have reduced miscarriage risk, while specific occupational characteristics such as crouching may have increased risk in this cohort.
Biological-effects; Ergonomics; Exposure-assessment; Exposure-levels; Exposure-methods; Job-analysis; Occupational-exposure; Physical-reactions; Physical-stress; Physiological-effects; Physiological-factors; Physiological-measurements; Physiological-response; Physiological-stress; Reproduction; Reproductive-effects; Reproductive-hazards; Reproductive-system; Statistical-analysis; Women; Work-environment; Worker-health;
Author Keywords: miscarriage; physical activity; occupation; reproductive; textile
E.Y. Wong, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024
American Journal of Industrial Medicine
Fred Hutchinson Cancer Research Center